Research teams participating in this project use various experimental and clinical approaches. The principle topics include:

• Mechanisms of neuroplasticity.
• Electrophysiological study of excitatory and inhibitory mechanisms.
• Behavioural changes and cognitive function following medication and brain injury.
• Relationship between iono- and metabotropic receceptors.
• Development of the new diagnostic a treatment methods for the orofacial pain.
• Computational Neuroscience

Research teams from following departments and institutes of the First Faculty of Medicine participate in the project:

• Fyziologický ústav | Institute of Physiology
• Klinika anesteziologie, resuscitace a intenzivní medicíny | Department of Anesthesiology and Intensive Care
• Neurochirurgická a neuroonkologická klinika |

Project coordinator: doc., MUDr. Vladimír Riljak. PhD.